Concise Review: Cellular Senescence, Receptor Dysfunction, Faulty Wound Healing

Chronic wounds are associated with very unique intracellular and extracellular/ ECM interactions both in cellular senescence and in growth factor deficiency but also with receptor dysfunction. Integrins are the main cellular receptors that mediate cell-ECM interaction and cell-cell mediated interactions. They anchor cells to their surrounding environment and transduce a variety of signals that influence […]